The arrests came after Big Spring Police searched a home in the 1600 block of Lark Street around 5:30 pm Tuesday.
A narcotics unit found about 2.5 pounds of cocaine and $78,000 cash at the home. The drugs, cash and four vehicles were seized by police
Police arrested Gabriel Aguilar -- who lived at the house -- and Jessee DeLeon.
Aguilar, 34, is charged with delivering a controlled substance (more than 400 grams), while DeLeon, 43, is charged with possession of a controlled substance (4 to 200 grams).
Police say the search warrant came at the end of a year-long investigation into cocaine distribution in Big Spring.